gbanyan ee27f3ad2f feat(02-02): add DuckDB loader and CLI evidence command for gnomAD ...

- load_to_duckdb: Saves constraint DataFrame to gnomad_constraint table with provenance tracking
- query_constrained_genes: Queries constrained genes by LOEUF threshold (validates GCON-03 interpretation)
- evidence_cmd.py: CLI command group with gnomad subcommand (fetch->transform->load orchestration)
- Checkpoint-restart: Skips processing if gnomad_constraint table exists (--force to override)
- Full CLI: usher-pipeline evidence gnomad [--force] [--url URL] [--min-depth N] [--min-cds-pct N]

2026-02-11 18:19:07 +08:00

..

__init__.py

feat(01-04): add CLI entry point with setup and info commands

2026-02-11 16:39:50 +08:00

evidence_cmd.py

feat(02-02): add DuckDB loader and CLI evidence command for gnomAD

2026-02-11 18:19:07 +08:00

main.py

feat(02-02): add DuckDB loader and CLI evidence command for gnomAD

2026-02-11 18:19:07 +08:00

setup_cmd.py

feat(01-04): add CLI entry point with setup and info commands

2026-02-11 16:39:50 +08:00