# Project State ## Project Reference See: .planning/PROJECT.md (updated 2026-02-11) **Core value:** Produce a high-confidence, multi-evidence-backed ranked list of under-studied cilia/Usher candidate genes that is fully traceable — every gene's inclusion is explainable by specific evidence, and every gap is documented. **Current focus:** Phase 1 - Data Infrastructure ## Current Position Phase: 1 of 6 (Data Infrastructure) Plan: 3 of 4 in current phase Status: Executing Last activity: 2026-02-11 — Completed 01-03-PLAN.md (DuckDB persistence and provenance tracking) Progress: [███░░░░░░░] 25.0% (1/6 phases planned, 2/4 plans in phase 1 complete) ## Performance Metrics **Velocity:** - Total plans completed: 2 - Average duration: 2.5 min - Total execution time: 0.08 hours **By Phase:** | Phase | Plans | Total | Avg/Plan | |-------|-------|-------|----------| | 01 - Data Infrastructure | 2/4 | 5 min | 2.5 min/plan | ## Accumulated Context ### Decisions Decisions are logged in PROJECT.md Key Decisions table. Recent decisions affecting current work: - Python over R/Bioconductor for rich data integration ecosystem - Weighted rule-based scoring over ML for explainability - Public data only for reproducibility - Modular CLI scripts for flexibility during development - Virtual environment required for dependency isolation (01-01: PEP 668 externally-managed Python) - Auto-creation of directories on config load (01-01: data_dir, cache_dir field validators) - [Phase 01-data-infrastructure]: DuckDB over SQLite for DataFrame storage (native polars/pandas integration, better analytics) - [Phase 01-data-infrastructure]: Provenance sidecar files alongside outputs (co-located metadata, bioinformatics standard pattern) ### Pending Todos None yet. ### Blockers/Concerns None yet. ## Session Continuity Last session: 2026-02-11 - Plan execution Stopped at: Completed 01-03-PLAN.md Resume file: .planning/phases/01-data-infrastructure/01-03-SUMMARY.md