cfe4b830e6
docs(03-03): complete protein features plan with SUMMARY and STATE updates
2026-02-11 19:10:03 +08:00
053f0d926b
docs(03-05): complete animal model phenotype evidence layer plan
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- SUMMARY.md: Ortholog-mapped animal evidence from MGI/ZFIN/IMPC
- Confidence-weighted scoring (mouse +0.4, zebrafish +0.3, IMPC +0.3)
- 14/14 tests passing: ortholog confidence, keyword filtering, NULL preservation
- Deviations: Schema mismatches, NULL handling, polars deprecations auto-fixed
- Duration: 10 minutes, 2 tasks, 8 files, 2 commits
2026-02-11 19:08:45 +08:00
d8009f1236
docs(03-04): complete subcellular localization evidence layer
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- Created SUMMARY.md with full implementation details
- Updated STATE.md: progress 40%, 8/20 plans complete
- Documented 4 key decisions (evidence terminology, NULL semantics, embedded proteomics, evidence weighting)
- All verification criteria met: 17/17 tests pass, CLI functional, DuckDB integration complete
2026-02-11 19:08:01 +08:00
99bc975a2c
docs(03-01): complete annotation completeness plan
2026-02-11 19:05:56 +08:00
0d252da348
docs(03): create phase plan
2026-02-11 18:46:28 +08:00
3354cfe006
docs(phase-03): research core evidence layers domain
2026-02-11 18:37:14 +08:00
ffb4963d2b
docs(phase-02): complete phase execution
2026-02-11 18:28:13 +08:00
a0388cf4e1
docs(02-02): complete gnomAD evidence layer integration plan
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- DuckDB persistence: gnomad_constraint table with CREATE OR REPLACE (idempotent)
- CLI evidence command: usher-pipeline evidence gnomad with checkpoint-restart
- Provenance tracking: records processing steps, saves sidecar JSON
- Query helpers: query_constrained_genes validates GCON-03 interpretation
- 12 integration tests: end-to-end pipeline, checkpoint, provenance, CLI
- Phase 2 complete: Evidence layer pattern established for future sources
- Duration: 4 min, 2 tasks, 5 files, 70 tests passing
Phase 2 (Prototype Evidence Layer) complete.
2026-02-11 18:23:32 +08:00
c6198122ac
docs(02-01): complete gnomAD constraint data pipeline plan
2026-02-11 18:16:35 +08:00
c7753e7b1c
docs(02): create phase plan
2026-02-11 17:47:23 +08:00
d328467737
docs(phase-02): research prototype evidence layer
2026-02-11 17:41:35 +08:00
34437fdf0a
docs(phase-01): complete phase execution
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Phase 1 (Data Infrastructure) verified: 5/5 must-haves, 12/12 artifacts,
9/9 key links, 7/7 requirements satisfied. All 4 plans executed across
3 waves with 49 tests passing.
Co-Authored-By: Claude Opus 4.6 <noreply@anthropic.com >
2026-02-11 16:50:30 +08:00
102dcdbe84
docs(01-04): complete CLI integration and end-to-end testing plan
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- CLI entry point with setup and info commands
- Full infrastructure integration verified
- 6 integration tests with mocked APIs
- Phase 01 Data Infrastructure complete
2026-02-11 16:45:12 +08:00
e29d39d1dc
docs(01-02): complete gene ID mapping and validation plan
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- Gene universe definition with mygene protein-coding gene retrieval
- Batch Ensembl->HGNC+UniProt mapping with edge case handling
- Validation gates with configurable success rate thresholds
- 15 comprehensive tests with mocked API responses
2026-02-11 16:35:57 +08:00
92322b1d7c
docs(01-03): complete DuckDB persistence and provenance tracking plan
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Co-Authored-By: Claude Opus 4.6 <noreply@anthropic.com >
2026-02-11 16:34:00 +08:00
9ee3ec2e84
docs(01-01): complete project scaffold and config system plan
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- Created comprehensive SUMMARY.md with all execution details
- Updated STATE.md: 1/4 plans in phase 1 complete, 16.7% overall progress
- Documented deviation (venv creation) and decisions
- Verified all files and commits exist (self-check passed)
2026-02-11 16:28:03 +08:00
cab2f5fc66
docs(01-data-infrastructure): create phase plan
2026-02-11 16:04:42 +08:00
982f7f5a9b
docs(01-data-infrastructure): research phase domain
2026-02-11 15:56:40 +08:00
