2 Commits

Author	SHA1	Message	Date
gbanyan	b151faa80a	docs: update top20 analysis with 93.8% gnomAD coverage results ... Reflects improved gnomAD gene_symbol fallback (+3,471 genes). Adds dual ranking (≥3 vs ≥4 layers) to address normalization inflation. New high-priority candidates: ARL3 (52% cilia literature), HDAC6 (known ciliogenesis regulator). HIGH tier: 82 genes. Co-Authored-By: Claude Opus 4.6 <noreply@anthropic.com>	2026-02-16 05:58:36 +08:00
gbanyan	13bba55ac7	docs: add top 20 candidate gene analysis with full 6-layer evidence ... Detailed analysis of top candidates from complete pipeline run with gnomAD constraint, tissue expression, annotation, localization, animal model, and literature evidence. Includes per-gene evidence breakdown, biological interpretation, and prioritized recommendations for follow-up. Co-Authored-By: Claude Opus 4.6 <noreply@anthropic.com>	2026-02-16 05:34:13 +08:00